B7-DC/CD273 （C-Fc）

簡(jiǎn)要描述：愛(ài)必信特色產(chǎn)品線（全部現(xiàn)貨）：
二抗、標(biāo)簽抗體、對(duì)照抗體；WB相關(guān)：ECL發(fā)光液、預(yù)染marker、預(yù)制膠；IHC相關(guān)：二抗試劑盒、組化筆；IP/CoIP試劑盒；細(xì)胞因子、信號(hào)通路調(diào)節(jié)劑；血清、BSA、蛋白酶K、CTB、TTX、CEE；凋亡試劑盒、呼吸爆發(fā)試劑盒；動(dòng)植物提取物...

產(chǎn)品型號(hào)：abs04042
廠商性質(zhì)：生產(chǎn)廠家
更新時(shí)間：2024-07-08
訪問(wèn) 量：2342

產(chǎn)品咨詢(xún)聯(lián)系我們

產(chǎn)品分類(lèi)

Product Category

細(xì)胞生物學(xué)

重組蛋白原代細(xì)胞分離細(xì)胞培養(yǎng) 細(xì)胞檢測(cè) 細(xì)胞/組織處理外泌體研究其它動(dòng)物血清 3D/類(lèi)器官培養(yǎng)

查看全部

相關(guān)文章

詳細(xì)介紹

品牌	absin	規(guī)格	10ug
供貨周期	一周

概述
描述	Recombinant Mouse Programmed Cell Death 1 Ligand 2 is produced by our Mammalian expression system and the target gene encoding Leu20-Arg219 is expressed with a Fc tag at the C-terminus.
別名	Programmed cell death 1 ligand 2,Pdcd1lg2,PD-1 ligand 2,PD-L2, PDCD1 ligand 2, B7-DC, CD273,
形態(tài)	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
來(lái)源	Human Cells
氨基酸序列	LFTVTAPKEVYTVDVGSSVSLECDFDRRECEGIRASLQKVENDTSLQSERATLLEEQLPLGK ALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYP LAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRME PKVPRVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDV SHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAP IEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPP VLDSDGSFFLYSKLTVDKSRWGNVFSCSVMHEALHNHYTQKSLSLSPGK
內(nèi)毒素水平	Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #	Q9WUL5

性能
背景	Programmed cell death 1 ligand 2 (PD-L2), also known as butyrophilin B7-DC or PDCD1 ligand 2, belongs to the member of B7 family which can regulate the activation and tolerance of T cells. PD-L2 is one ligand for Programmed cell death 1(PD-1), and the other is PD-L1. These two ligands shares 34% aa sequence identity. Mouse PD-L2 gene encodes a 273 amino acids (aa) protein with a putative 19 aa signal peptide, a 201 aa extracellular region , a 21 aa transmembrane domain and a 32 aa cytoplasmic region. The mouse PD-L2 gene is highly expressed in heart, placenta, pancreas, lung and liver while expressed weakly in spleen, lymph nodes and thymus. Besides, the expression of PD-L2 gene can be induced on dendritic cells grown from peripheral blood mononuclear cells under CSF2 and IL4/interleukin-4 treatment, and up-regulated by IFNG/IFN-gamma stimulation in monocytes. PD-L2 usually functions in a PDCD1-independent manner and is involved in regulating costimulatory signal which is essential for T-cell proliferation and IFNG production. Recent studies demonstrate that the expression of PD-L2 on the tumor cells promotes CD8 T cell–mediated rejection of tumor cells, at both the induction and effector phase of antitumor immunity. Moreover, PD-L2 binds to PD-1 cells and enhances T cell killing in a PD-1–independent mechanism.
溶解方法	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度	Greater than 95% as determined by reducing SDS-PAGE.

產(chǎn)品咨詢(xún)

留言框

產(chǎn)品：
您的單位：
您的姓名：
聯(lián)系電話：
常用郵箱：
省份：
詳細(xì)地址：
補(bǔ)充說(shuō)明：
驗(yàn)證碼：

請(qǐng)輸入計(jì)算結(jié)果（填寫(xiě)阿拉伯?dāng)?shù)字），如：三加四=7

上一篇：abs04021CD32b/FCGR2 （C-6His）
下一篇：abs04041PD-1/CD279 （C-6His）

ririri国产在线观看_亚洲欧洲美洲无码精品va_国产精品自产拍高潮在线_91精品久久久老熟女九色91

B7-DC/CD273 （C-Fc）

留言框

產(chǎn)品：

您的單位：

您的姓名：

聯(lián)系電話：

常用郵箱：

省份：

詳細(xì)地址：

補(bǔ)充說(shuō)明：

驗(yàn)證碼：