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IL-21R (C-6His)

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  • 產(chǎn)品型號:abs04078
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2024-07-08
  • 訪  問  量:803

詳細介紹

品牌absin規(guī)格10ug
供貨周期一周
概述
描述Recombinant Human Interleukin-21 Receptor is produced by our Mammalian expression system and the target gene encoding Cys20-Pro236 is expressed with a 6His tag at the C-terminus.
別名Interleukin-21 receptor,IL-21 receptor, IL-21R, CD360.
形態(tài)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH 7.4.
來源Human Cells
氨基酸序列CPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYM LKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTW SEWSDPVIFQTQSEELKEGWNPVDHHHHHH
內(nèi)毒素水平Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #Q9HBE5
性能
背景Interleukin-21 receptor is also known as IL-21 receptor, IL-21R, CD360. In humans, it is encoded by the IL21R gene. It belongs to the type I cytokine receptor family. Type 4 subfamily contains 2 fibronectin type-III domains. Interleukin-21 receptor is selectively expressed in lymphoid tissues and highly expressed in thymus and spleen. IL-21 is produced by CD4+ T cells in response to antigenic stimulation. Its action enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells. It also promotes the anti-tumor activity of CD8+ T-cells and NK cells.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE. 

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