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首頁 > 產品中心 > 細胞生物學 > 重組蛋白 > abs04208FGF-19 (N-6His)(10ug)

FGF-19 (N-6His)(10ug)

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  • 產品型號:abs04208
  • 廠商性質:生產廠家
  • 更新時間:2024-07-08
  • 訪  問  量:766

詳細介紹

品牌absin貨號abs04208
規(guī)格10ug供貨周期一周
概述
描述Recombinant Human Fibroblast growth factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus.
別名Fibroblast growth factor 19, FGF-19, FGF19
形態(tài)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
來源E. coli
氨基酸序列MGSSHHHHHHSSGLVPRGSHMFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDC ARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYR SEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPF GLVTGLEAVRSPSFEK
內毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Accession #O95750
性能
背景Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE.

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愛必信(上海)生物科技有限公司
地址:上海市浦東新區(qū)新浩路58號申江科創(chuàng)園18棟
郵箱:wulan@absin.cn
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