Products產(chǎn)品中心

首頁 > 產(chǎn)品中心 > 生化試劑 > 小分子化合物 > CHIR-99021 trihydrochloride（2mg）

CHIR-99021 trihydrochloride（2mg）

簡要描述：愛必信特色產(chǎn)品線（全部現(xiàn)貨）：二抗、標(biāo)簽抗體、對照抗體；WB相關(guān)：ECL發(fā)光液、預(yù)染marker、預(yù)制膠；IHC相關(guān)：二抗試劑盒、組化筆；IP/CoIP試劑盒；細(xì)胞因子、信號通路調(diào)節(jié)劑；血清、BSA、蛋白酶K、CTB、TTX、CEE；凋亡試劑盒、呼吸爆發(fā)試劑盒；動植物提取物...

產(chǎn)品型號：
廠商性質(zhì)：生產(chǎn)廠家
更新時間：2024-07-07
訪問量：1556

產(chǎn)品咨詢聯(lián)系我們

產(chǎn)品分類

Product Category

生化試劑

其它生化試劑植物提取物碳水化合物生物緩沖劑氨基酸及衍生物熒光探針與染料表面活性劑酶&輔酶&酶底物蛋白質(zhì)組學(xué) 動植物激素小分子化合物生化檢測試劑盒逆行示蹤劑抗生素核苷&核苷酸多肽

查看全部

相關(guān)文章

詳細(xì)介紹

品牌	absin	貨號	abs818359
規(guī)格	2mg	供貨周期	現(xiàn)貨

概述
描述	CHIR-99021 trihydrochloride is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.

性能
純度	＞98%
分子量	574.72
化學(xué)式	C??H??Cl?N?
分子結(jié)構(gòu)式
溶解性	DMSO: ≥ 32 mg/mL
CAS號	1782235-14-6

參考文獻(xiàn)
[1]. Ring DB et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95. [2]. Weikel KA et al. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016 Sep 16;36(5). [3]. Ai Z et al. CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells. PLoS One. 2016 Mar 3;11(3) [4]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24. [5]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24.

參考文獻(xiàn)

[1]. Ring DB et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.

[2]. Weikel KA et al. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016 Sep 16;36(5).

[3]. Ai Z et al. CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells. PLoS One. 2016 Mar 3;11(3)

[4]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24.

[5]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24.

產(chǎn)品咨詢