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Recombinant Human TGFB3（10ug）

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  • 產(chǎn)品型號(hào)：abs04215
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2024-07-07
  • 訪  問  量：1132

詳細(xì)介紹

品牌absin貨號(hào)abs04215
規(guī)格10ug供貨周期一周
概述
描述Recombinant Human/Mouse Transforming Growth Factor beta 3 is produced by our Mammalian expression system and the target gene encoding Ala301-Ser412(Tyr340Phe) is expressed.
別名Transforming growth factor beta-3,TGFB3,TGF-beta-3,Latency-associated peptide,LAP
形態(tài)Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
來源Human Cells
氨基酸序列ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYFANFCSGPCPYLRSADTTHSTVLGLY NTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
內(nèi)毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Accession #P10600
性能
背景Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE.

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